Eagles vs. Chiefs Week 2 Predictions, Odds and Stats

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When the Philadelphia Eagles square off against the Kansas City Chiefs at 4:25 p.m. ET on Sunday, Sept. 14, our projection model predicts the Eagles will win the game. Our model also projects the spead, point total, and final score, which you can read below.

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Eagles vs. Chiefs Game Info and TV Channel

  • When: Sunday, September 14, 2025 at 4:25 p.m. ET
  • Where: GEHA Field at Arrowhead Stadium in Kansas City, Missouri
  • TV: FOX
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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Eagles vs. Chiefs Odds and Betting Info

  • Spread favorite: Eagles (-1)
  • Moneyline: Eagles (-120), Chiefs (+100)
  • Total: 47 points

Eagles vs. Chiefs Prediction

  • Pick ATS: Chiefs (+1)
  • Pick OU: Under (47)

Prediction:

Eagles 22 - Chiefs 21

    Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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    Eagles vs. Chiefs Betting Insights (2024 Stats)

    • The Eagles covered 11 times in 17 games with a spread last season.
    • The Chiefs covered seven times in 17 matchups with a spread last season.
    • When playing as at least 1-point favorites last season, Philadelphia had an ATS record of 8-6.
    • Kansas City covered the spread once when an underdog by 1 point or more last year (in three opportunities).
    • Last season, the combined scoring went over the point total seven times in Eagles games.
    • The Chiefs and their opponent combined to go over the point total seven out of 17 times last season.

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