According to our computer projection model, the Philadelphia Eagles will beat the Los Angeles Rams when the two teams come together at Lincoln Financial Field on Sunday, Sept. 21, which starts at 1 p.m. ET. For our predictions on the spead, point total, and final score, check out the rest of the article below.
Don't miss a touchdown this NFL season. Catch every score with NFL RedZone on Fubo. What is Fubo? Fubo is a streaming service that gives you access to your favorite live sports and shows on demand. Sign up today and watch seven hours of football from every NFL game every Sunday.
Eagles vs. Rams Game Info and TV Channel
- When: Sunday, September 21, 2025 at 1 p.m. ET
- Where: Lincoln Financial Field in Philadelphia, Pennsylvania
- TV: FOX
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
Catch every NFL touchdown with NFL RedZone on Fubo.
Listen to the game on
Eagles vs. Rams Odds and Betting Info
- Spread favorite: Eagles (-3.5)
- Moneyline: Eagles (-187), Rams (+157)
- Total: 44.5 points
Eagles vs. Rams Prediction
- Pick ATS: Eagles (-3.5)
- Pick OU: Under (44.5)
Prediction:
Eagles 28 - Rams 16
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
See how these predictions pan out and sign up for NFL RedZone on Fubo to catch every score on Sundays this fall.
Eagles vs. Rams Betting Insights
- The Eagles have a record of 1-1-0 against the spread this season.
- The Rams have won two games against the spread this year.
- Philadelphia has not covered the spread this season (0-1 ATS) when playing as at least 3.5-point favorites.
- The Eagles and their opponent have not hit the over yet this season.
- Games featuring the Rams have gone over the point total once this year.
Looking for NFL tickets? Head to StubHub today and see your team live.