Philadelphia has a 22-18-0 record against the spread this season.
In games they have played as at least 5.5-point favorites this season, the 76ers are 5-3 against the spread.
In Philadelphia's 43 games with a set total, 21 have hit the over (48.8%).
The 76ers have been favorites in 25 games this season and won 17 (68%) of those contests.
Philadelphia has a record of 3-2 when it's favored by -228 or more by oddsmakers this season.

Indiana is 22-21-0 ATS this season.
The Pacers have a 12-11 record against the spread when an underdog by 5.5 points or more this season.
Of Indiana's 43 games with a set total, 16 have hit the over (37.2%).
The Pacers have a 7-29 record in games they were the underdog on the moneyline (winning 19.4% of those games).
When it has played as a moneyline underdog with odds of +188 or longer, Indiana has gone 2-19 (9.5%).

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76ers:

Paul George: Questionable (Knee),

Joel Embiid: Questionable (Knee)

Pacers:

Obi Toppin: Out (Foot),

Tyrese Haliburton: Out For Season (Achilles),

Bennedict Mathurin: Out (Thumb)

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